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The company’s main area of focus is cystic fibrosis (CF). The company’s lead marketed products are Trikafta (elexacaftor/tezacaftor/ivacaftor and ivacaftor), Symdeko/Symkevi (tezacaftor in combination with ivacaftor), Orkambi (lumacaftor in combination with ivacaftor) and Kalydeco (ivacaftor), which are collectively approved to treat the majority of the people with CF in North America, Europe and Australia. Trikafta, Vertex’s triple combination regimen, was approved by the FDA in October 2019 for the treatment of CF in people aged 12 years and older who have at least one F508del mutation. Kaftrio (brand name of Trikafta in EU) was approved in the European Union in August 2020. It is also being evaluated in younger patients in the United States. With approval of Trikafta, Vertex can address a significantly larger CF patient population — almost 90% of patients with CF — in the future. Meanwhile, Vertex is pursuing genetic therapies to address the remaining 10% of CF patients. While CF remains the main area of focus, Vertex is also developing treatments for sickle cell disease, thalassemia and pain management.
Vertex Pharmaceuticals (VRTX) Stock Moves -1.86%: What You Should Know
by Zacks Equity Research
Vertex Pharmaceuticals (VRTX) closed at $254.88 in the latest trading session, marking a -1.86% move from the prior day.
Vertex (VRTX) Kidney Drug Gets FDA Breakthrough Designation
by Zacks Equity Research
Vertex (VRTX) inaxaplin is being evaluated in a single-phase II/III pivotal study in patients with AMKD with two APOL1 mutations and proteinuric kidney disease.
Is Invesco Dynamic Biotechnology & Genome ETF (PBE) a Strong ETF Right Now?
by Zacks Equity Research
Smart Beta ETF report for PBE
The Zacks Analyst Blog Highlights Alibaba, McDonald, Advanced Micro Devices, Abbott Laboratories, and Vertex Pharmaceuticals
by Zacks Equity Research
Alibaba, McDonald, Advanced Micro Devices, Abbott Laboratories, and Vertex Pharmaceuticals are part of the Zacks top Analyst Blog.
Top Stock Reports for Alibaba, McDonald's & Advanced Micro Devices
by Sheraz Mian
Today's Research Daily features new research reports on 16 major stocks, including Alibaba Group Holding Limited (BABA), McDonald's Corporation (MCD), and Advanced Micro Devices, Inc. (AMD).
Vertex (VRTX) Outperforms Industry This Year So Far: Here's Why
by Zacks Equity Research
Vertex's (VRTX) cystic franchise sales continue to grow. Vertex has a broad clinical non-CF pipeline, which is progressing rapidly.
CRISPR (CRSP) Focuses on Pipeline Amid Lack of Marketed Drugs
by Zacks Equity Research
While CRISPR Therapeutics' (CRSP) lead candidate is still a couple of years away from commercialization, it is highly dependent on collaboration revenues to fund its ongoing pipeline.
Should You Invest in the VanEck Biotech ETF (BBH)?
by Zacks Equity Research
Sector ETF report for BBH
The Zacks Analyst Blog Highlights Regeneron, Vertex, Intercept Pharmaceuticals, and Biohaven Pharmaceutical
by Zacks Equity Research
Regeneron, Vertex, Intercept Pharmaceuticals, and Biohaven Pharmaceutical are part of Zacks top Analyst Blog
Biotech Stock Roundup: REGN, VRTX Earnings Update, BHVN Up on Regulatory News
by Ekta Bagri
Earnings and regulatory updates from Regeneron (REGN) and Vertex (VRTX) are a few key highlights from the biotech sector during the past week.
Amicus (FOLD) Q1 Earnings Miss, Galafold Sales Top Estimates
by Zacks Equity Research
Amicus Therapeutics (FOLD) posts a wider-than-expected loss for the first quarter. FOLD's sole marketed drug Galafold's solid sales drive the top line.
CRISPR Therapeutics (CRSP) Q1 Earnings & Sales Miss Estimates
by Zacks Equity Research
CRISPR Therapeutics (CRSP) reports wider-than-expected Q1 loss. Revenues miss estimates.
Intercept (ICPT) Q1 Earnings Top, Ocaliva Sales Miss Estimates
by Zacks Equity Research
Intercept (ICPT) posts a narrower-than-expected loss in the first quarter. Sales lag estimates.
Viatris' (VTRS) Q1 Earnings Beat, Revenues Miss Estimates
by Zacks Equity Research
Viatris (VTRS) beats on Q1 earnings but misses sales estimates. The company is on track to close its biosimilars deal with Biocon Biologics in the second half.
Alcon (ALC) to Report Q1 Earnings: What's in the Cards?
by Zacks Equity Research
Strength in Vision Care with the addition of new products and recent acquisition is likely to have contributed to Alcon's (ALC) first-quarter performance.
Endo (ENDP) Beats on Q1 Earnings, Guides Weak Q2 Results
by Zacks Equity Research
Endo (ENDP) tops Q1 earnings and sales estimates. However, Vasostrict faces generic competition and the guidance for Q2 is dismal.
Radius (RDUS) Q1 Loss Wider Than Expected, Revenues Decline
by Zacks Equity Research
Radius (RDUS) posts a y/y wider Q1 loss and misses revenue estimates.
Ultragenyx's (RARE) Q1 Earnings & Revenues Miss Estimates
by Zacks Equity Research
Ultragenyx (RARE) reports wider-than-expected loss in the first quarter of 2022 while revenues miss estimates.
Deciphera (DCPH) Down Despite Narrower-Than-Expected Q1 Loss
by Zacks Equity Research
Deciphera (DCPH) reports narrower-than-expected loss in the first quarter of 2022 while revenues beat estimates.
STERIS (STE) to Report Q4 Earnings: What's in the Cards?
by Zacks Equity Research
Strength in Healthcare and AST arms is expected to have driven STERIS' (STE) fourth-quarter revenues.
Vertex (VRTX) Q1 Earnings Lag, Sales Top, Expense View Tweaked
by Zacks Equity Research
Vertex Pharmaceuticals' (VRTX) earnings miss estimates while sales beat the same for the first quarter of 2022. The company maintains its revenue guidance for 2022.
Apellis (APLS) Hit By Wider-Than-Expected Q1 Loss, Revenues Top
by Zacks Equity Research
Apellis' (APLS) earnings missed estimates in the first quarter of 2022, while revenues surpassed expectations.
Is Lantheus (LNTH) Outperforming Other Medical Stocks This Year?
by Zacks Equity Research
Here is how Lantheus Holdings (LNTH) and Vertex Pharmaceuticals (VRTX) have performed compared to their sector so far this year.
Vertex Pharmaceuticals (VRTX) Q1 Earnings Miss Estimates
by Zacks Equity Research
Vertex (VRTX) delivered earnings and revenue surprises of -2.22% and 0.79%, respectively, for the quarter ended March 2022. Do the numbers hold clues to what lies ahead for the stock?
Global Blood (GBT) Q1 Loss Narrower Than Expected, Revenues Lag
by Zacks Equity Research
Global Blood Therapeutics (GBT) reports y/y wider loss in Q1. Revenues witness a rise.