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biotechs: Archive

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Regeneron (REGN) Posts Positive Data on Blood Cancer Candidate

Regeneron's (REGN) multiple myeloma candidate demonstrates strong rates and depth of response in pre-treated patients.

REGNPositive Net Change RHHBYPositive Net Change DVAXPositive Net Change TRDAPositive Net Change

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Merck's (MRK) Keytruda-Lynparza Combo Fails Lung Cancer Study

After a late-stage study fails to show any improvement in its primary endpoints, Merck (MRK) decides to stop evaluating the Keytruda-Lynparza combination in metastatic squamous NSCLC.

AZNNegative Net Change NVONegative Net Change MRKPositive Net Change CTMXPositive Net Change

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Kymera (KYMR) Rises as Dosing Begins in AD Study on KT-474

Kymera (KYMR) receives a $15 million milestone payment from Sanofi as dosing begins in a phase II study evaluating KT-474 for treating atopic dermatitis. Shares rise on the same.

SNYPositive Net Change PBYINegative Net Change KYMRPositive Net Change TRDAPositive Net Change

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Solid Biosciences' (SLDB) DMD Drug Gets Fast Track Tag, Stock Up

Solid Biosciences (SLDB) gains 68% as the FDA grants Fast Track designation to the company's gene therapy candidate, SGT-003, for the treatment of Duchenne muscular dystrophy.

RHHBYPositive Net Change SRPTPositive Net Change PTCTNegative Net Change SLDBNegative Net Change

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Pharvaris (PHVS) Stock Up 18% on HAE Drug Meeting Study Goal

Data from a mid-stage study shows that treatment with Pharvaris' (PHVS) investigational HAE drug reduced the monthly attack rate by 84.5%.

BCRXNo Net Change NVONegative Net Change IONSPositive Net Change PHVSPositive Net Change

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Sanofi (SNY) Posts Upbeat Long-Term Outlook, Enhances R&D Focus

Sanofi (SNY) aims to generate annual sales of over 10 billion euros by 2030, driven by recently launched and potential new products. It intends to enhance R&D focus to become a market leader in immunology.

REGNPositive Net Change SNYPositive Net Change AZNNegative Net Change NVONegative Net Change

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Century (IPSC) Up 36% on FDA Nod to Begin Phase I Lupus Study

Century (IPSC) set to begin early-stage study on lead product candidate, CNTY-101, for treatment of systemic lupus erythematosus following IND clearance by FDA. The stock rises 36%.

AGENPositive Net Change PBYINegative Net Change ADMANegative Net Change IPSCPositive Net Change

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Syros (SYRS) Rises on Upbeat Initial Study Data on Tamibarotene

Syros (SYRS) posts encouraging initial data from the phase II SELECT-AML-1 study evaluating tamibarotene in combination with venetoclax and azacitidine to treat acute myeloid leukemia.

PBYINegative Net Change AQSTPositive Net Change TRDAPositive Net Change

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Biotech Stock Roundup: EXEL Partners RCUS for Study, PHVS & EYPT Gain on Study Data

Updates from Exelixis (EXEL) and Pharvaris (PHVS) are in the spotlight this week.

BMYPositive Net Change EXELPositive Net Change EYPTPositive Net Change RCUSPositive Net Change PHVSPositive Net Change

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Dr. Reddy's (RDY), COYA Ink Deal to Develop COYA 302 for ALS

Dr. Reddy's (RDY) enters into a licensing agreement with Coya Therapeutics to develop and commercialize the latter's ALS investigational combination therapy, COYA 302.

RDYPositive Net Change AGENPositive Net Change PBYINegative Net Change COYANegative Net Change

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AbbVie (ABBV) to Acquire Cerevel Therapeutics (CERE) for $8.7B

AbbVie (ABBV) offers to buy Cerevel Therapeutics (CERE) for $8.7 billion. The acquisition will strengthen AbbVie's neuroscience pipeline.

NVONegative Net Change IMGNPositive Net Change ABBVNegative Net Change CEREPositive Net Change

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Travere (TVTX) Up on Latest Portfolio Updates & Reorganization

Travere (TVTX) to submit an sNDA to the FDA to convert the accelerated approval for Filspari to full approval for IgAN in first-quarter 2024. The company is implementing a strategic reorganization to cut costs. Stock rises.

PBYINegative Net Change TVTXPositive Net Change AVTXPositive Net Change TRDAPositive Net Change

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ImmunoGen (IMGN) Gets FDA Priority Review for Elahere sBLA

The FDA grants priority review to ImmunoGen's (IMGN) sBLA to convert the accelerated approval for Elahere to full approval for treating platinum-resistant ovarian cancer. A decision is due on Apr 5, 2024.

IMGNPositive Net Change ABBVNegative Net Change HARPNegative Net Change AVTXPositive Net Change

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Pfizer (PFE), Arvinas Post Upbeat Data From Breast Cancer Study

Interim data from an early-stage study shows that treatment with Pfizer (PFE)/Arvinas' (ARVN) breast cancer combination therapy demonstrates encouraging clinical activity in heavily pre-treated patients.

PFEPositive Net Change NVONegative Net Change CTMXPositive Net Change ARVNPositive Net Change

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Bristol Myers' (BMY) Opdivo sBLA Gets FDA's Priority Review

Bristol Myers (BMY) announces that the FDA has accepted its sBLA for Opdivo to treat first-line adult patients with unresectable or metastatic bladder cancer under priority review.

BMYPositive Net Change AGENPositive Net Change PBYINegative Net Change ADMANegative Net Change

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Exelixis (EXEL) Collaborates With Arcus for Kidney Cancer Study

Exelixis (EXEL) partners with Arcus Biosciences for a phase Ib/II study to evaluate zanzalintinib in combination with AB521 for ccRCC.

BMYPositive Net Change MRKPositive Net Change EXELPositive Net Change RCUSPositive Net Change

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Roche (RHHBY) Breast Cancer Drug Meets Primary Goal in Phase III

Roche's (RHHBY) phase III study evaluating inavolisib in combination with advanced hormone receptor-positive, HER2-negative breast cancer with a PIK3CA mutation achieves its primary goal.

RHHBYPositive Net Change DVAXPositive Net Change PFEPositive Net Change TRDAPositive Net Change

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Alterity (ATHE) Up on Preclinical Parkinson's Treatment Data

Data from a preclinical study shows that treatment with Alterity's (ATHE) lead candidate improved motor performance and general function in monkeys with experimentally-induced Parkinson's disease.

NVONegative Net Change PBYINegative Net Change CTMXPositive Net Change ATHENegative Net Change

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CRISPR (CRSP) to Focus on Next-Generation CAR T Pipeline

Based on early data from ongoing clinical studies, CRISPR (CRSP) has decided to focus on the development of its next-generation CAR T pipeline and discontinue its first-generation CAR T candidates.

NVONegative Net Change VRTXNegative Net Change CTMXPositive Net Change CRSPPositive Net Change

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EyePoint (EYPT) Surges 178% on Upbeat Phase II Eye Disease Data

EyePoint (EYPT) announces positive top-line data from the phase II study of its investigational candidate, EYP-1901, in the treatment of wet age-related macular degeneration. The stock rallies 178%.

REGNPositive Net Change BAYRYNegative Net Change EYPTPositive Net Change KODPositive Net Change

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Vanda (VNDA) Rises as FDA Accepts NDA for Gastroparesis Drug

The FDA accepts Vanda's (VNDA) new drug application ("NDA") for tradipitant for treating the symptoms of gastroparesis. The company's shares rise in after-hours trading.

PBYINegative Net Change VNDANegative Net Change CTMXPositive Net Change TRDAPositive Net Change

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Absci (ABSI) Up on AstraZeneca Deal to Design New Cancer Therapy

Absci (ABSI) announces a collaboration agreement with AstraZeneca to develop an AI-designed antibody for an undisclosed oncology target. The stock rises 13%.

AZNNegative Net Change MRNAPositive Net Change IMTXPositive Net Change ABSIPositive Net Change

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Is it a Good Idea to Invest in AC Immune (ACIU) Stock Now?

Here, we discuss some reasons why investing in AC Immune (ACIU) stock now may turn out to be a prudent move.

LLYNegative Net Change PBYINegative Net Change CTMXPositive Net Change ACIUPositive Net Change

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Lilly (LLY) Gets Second FDA Nod for Lymphoma Drug Jaypirca

Following the latest approval, Lilly's (LLY) Jaypirca is the first and the only non-covalent BTK inhibitor to extend the benefit of targeting the BTK pathway.

AZNNegative Net Change JNJNegative Net Change LLYNegative Net Change ABBVNegative Net Change

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Altimmune (ALT) Rises 83% on Successful Phase II Obesity Study

Altimmune (ALT) reports positive top-line data from its 48-week phase II MOMENTUM study of obesity drug candidate, pemvidutide. The stock gains 83%.

PFEPositive Net Change NVONegative Net Change LLYNegative Net Change ALTPositive Net Change